Figure 8: Visualizing Cancer. Imaging is an increasingly essential part of modern cancer care, from routine screening and prevention to
informing diagnoses. More recently, imaging is being used to monitor response to therapy both in the clinic and during drug discovery. Not all
imaging, however, provides the same quantity or type of information. In the example shown, a routine mammography (A, mammogram) detected
no cancer, while MRI detected a tumor in the same breast (A, MRI) (143). Likewise, in this example FDG-PET revealed a bone metastasis (D, FDG-PET), whereas the CT scan did not (D, CT) and the MRI analysis was unclear (D, MRI) (144). New types of imaging like FDG-PET are better able to
detect metastases (B, day 1) and show the patient’s tumor’s rapid response to therapy (B, day 4) (145). Increasingly, different types of imaging are
being combined to provide the most complete information possible. For example, the use of double contrast–MRI together with FDG-PET (C)
reveals the precise location and size of the tumor (146).